St. Louis University researchers have received a three-year, $1 million grant from the Centers of Disease Control to expand their education of doctors about the risks of drinking during pregnancy and fetal alcohol syndrome.

“Drinking during pregnancy increases the risk of birth defects, which have lifelong consequences and can easily be prevented,” said Leigh Tenkku, an assistant professor of family and community medicine at the university. “It is very important to get the message out to health care professionals and to include this information in academic training settings.”

Research has shown that advice from doctors and nurses is one of the most influential factors in determining whether or not women drink during pregnancy. Yet many health care professionals are uncomfortable talking to their patients about alcohol use, are unsure about current guidelines or lack the necessary resources, Tenkku said.

“Only 50 percent of health care providers give information about the consequences of drinking during pregnancy to all patients,” Tenkku said. “Our goal is to educate as many health care professionals as possible about the very real dangers posed by drinking during pregnancy and enable them to help their patients.

In 2002, St. Louis University worked with the University of Missouri–Columbia and St. Louis Arc to establish the Midwest Regional Fetal Alcohol Syndrome Training Center to educate health care professionals and students. The grant will allow the center to set up satellite faculty teams in each of the eight Midwest states served by the center, including Illinois. (…)

Source: Belleville News Democrat, USA
http://www.bnd.com/living/health/story/529994.html

We now have new evidence, after the publication of a study in Human Reproduction, that women who are severely depressed during pregnancy are at much higher risk of giving birth prematurely.

The recent report is one of a handful of scientific studies to document the association between maternal depression and premature birth. But it’s the most important to date because of its size and the large, representative group of women sampled.

Previous research suggests that 9 to 12 percent of women become clinically depressed during pregnancy. The question, of course, is why a mother’s mental state would affect the timing of a birth.

No one knows for sure. But experts speculate that depression affects a woman’s neuroendocrine system, which in turn affects the hormones circulating in her body, which in turn affects the functioning of the placenta that nourishes the infant.

“To sustain a healthy pregnancy, normal placental function is essential,” said Dr. De-Kun Li, a reproductive and perinatology epidemiologist at Kaiser Permanente in Northern California and lead author of the report. “Potentially, depression can lead to malfunction of the placenta,” he suggested.

Indeed, there is increasing evidence that something along these lines occurs with women who experience stress during pregnancy.

Dr. Diane Ashton, deputy medical director for the March of Dimes, notes that stress can alter a woman’s immune function, leading to “increased susceptibility to intra-amniotic infection or inflammation.” Research studies indicate these infections may play an important role in pre-term births.

Also, Ashton says, maternal stress can jump-start the production of “fight or flight” hormones like cortisol, which in turn can prematurely activate placental hormones that can set off a cascade of events leading to premature birth.

Even if a baby is born full term, being bathed in cortisol in utero can affect fetal brain development, research shows.

Dr. Laura Miller, director of the women’s mental health program at the University of Illinois at Chicago Medical Center, said research shows that children of stressed-out pregnant women can be affected at least to age 10.

These children often have hyper-reactive responses, physiologically and emotionally, and have “greater difficulty dealing with stress,” she says. Also, infants of stressed mothers can be “more irritable and difficult to soothe” and demonstrate “poorer growth and increased risk of infection,” she notes.

As for maternal depression, it may operate through similar mechanisms – by altering similar hormones and producing similar physiological responses – or it may not. The research necessary to clarify what’s happening hasn’t yet been done.

We don’t know, either, if it makes a difference at what point during a pregnancy a mom becomes depressed (the Human Reproduction report studied only moms who reported depressed symptoms in the first trimester) or how long the depression lasts.

Miller suggests the take-home message for moms is “depression during pregnancy can be prevented, and if a woman suspects she might be at risk she really should strongly consider pre-conception counseling.”

Factors that can put women at risk include previous bouts of depression and a family history of maternal depression.

For women who are considering pregnancy but have concerns about mental health, there are several therapeutic options, including psychotherapy, strengthening social supports, and medication, Miller notes. For those who become depressed during pregnancy, these options remain, but the profile of potential benefits and risks differs, depending on the type of depression a woman has and other factors.

Since surveys show that most ob/gyns don’t feel comfortable treating depression, it’s important to find a medical expert who is prepared to help. Be honest about what you’re feeling and ask your ob/gyn directly if she’s the right person to offer assistance.

Among the questions that Miller suggests: “Have you had experience treating depression during a pregnancy?” “Do you have special training in working with pregnant women who are depressed?” “Do you refer people with these kinds of problems to a psychiatrist – and, if so, can I get a referral?”

Source: Chicago Tribune, United States
http://newsblogs.chicagotribune.com/triage/2008/10/depression-and.html

Stress during pregnancy can have unfortunate consequences for children born under those conditions - slower development, learning and attention difficulties, anxiety and depressive symptoms and possibly even autism.

That such stress during a mother’s pregnancy can cause developmental and emotional problems for offspring has long been observed by behavioral and biological researchers, but the objective measuring and timing of that stress and its results are difficult to prove objectively in humans, since the evidence is based to a large extent on anecdotal recollections and is also strongly influenced by genetic and other factors.

One researcher who has long wrestled with the problem of how to prove the connection between prenatal stress and its effects on offspring is Prof. Marta Weinstock-Rosin of the Hebrew University of Jerusalem School of Pharmacy, who in her experimental work with rats has been able to demonstrate that relationship in a conclusive, laboratory-tested manner.

“There is an enormous advantage in working with rats,” says Weinstock-Rosen, “since we are able to eliminate the genetic and subjective element.” The researchers were able to compare the behavior of the offspring of stressed rat mothers with those whose mothers were not stressed. They also were able to compare the results of administering various types of stress at different periods during the gestation process to see which period is the most sensitive for the production of different behavioral alterations.

Weinstock-Rosin’s work, along with that of colleagues from Israel, the UK and elsewhere, will be presented at an international conference, “Long Term Consequences of Early Life Stress,” which she is co-chairing with Dr. Vivette Glover of the Imperial College, London, and that will be held at Mishkenot Sha’ananim in Jerusalem on October 29 and 30.

Weinstock-Rosin has been able to show through her laboratory experiments that when rat mothers were subject to stressful situations (irritating sounds at alternating times, for example), their offspring were later shown to have impaired learning and memory abilities, less capacity to cope with adverse situations (such as food deprivation), and symptoms of anxiety and depressive-like behavior, as compared to those rats in control groups that were born to unstressed mothers. All of these symptoms parallel the impairments that have been observed in children born to mothers who were stressed in pregnancy, she points out.

Further experiments by Weinstock-Rosin and her students have shown the crucial effect of excessive levels of the hormone cortisol that is released by the adrenal gland during stress and reaches the fetal brain during critical stages of brain development. Under normal conditions, this hormone has a beneficial function in supplying instant energy, but it has to be in small amounts and for a short period of time. Under conditions of excessive stress, however, the large amount of this hormone reaching the fetal brain can cause structural and functional changes. In humans, above-normal levels of cortisol can also stimulate the release of another hormone from the placenta that will cause premature birth, another factor that can affect normal development.

Weinstock-Rosin says that further experimental work is required in order to study possible other effects on the offspring resulting from raised hormonal levels. What does seem to be obvious already is that avoidance of stress to as great an extent as possible is a good prescription for a healthy pregnancy and healthy offspring.

Husbands take note!

Source: Medical News Today, HK
http://www.medicalnewstoday.com/articles/127086.php

Many new mothers battling with tiredness and struggling to carry out the simplest of tasks would beg to differ.

But according to scientists, giving birth supercharges brain power to equip women for the challenge of rearing their child.

Having a baby produces a sudden surge of memory and learning ability that makes them more vigilant and alert, a study concluded.

And the changes in the size and shape of many areas of the brain last for decades, protecting against degenerative diseases later in life.

Researchers found there was often a decline in mental powers during pregnancy as the minds of mothers-to-be are remodelled.

But hormonal fluctuations during birth and breastfeeding increase the size of cells in some areas of the brain leading to dramatic improvements in mental capacity.

Studies on animals including rats and primates found mothers become much braver, are up to five times faster at finding food and have better spatial awareness than those without offspring.

Craig Kinsley, professor of neuroscience at the University of Richmond, Virginia, said he believed the same results applied to humans. ‘Pregnant women do undergo a phase of so-called baby brain, when they experience an apparent loss of function,’ he said.

‘However, this is because their brains are being remodelled for motherhood to cope with the many new demands they will experience.

‘Many benefits seem to emerge from motherhood, as the maternal brain rises to the reproductive challenge. When the going gets tough, the brain gets going.

‘The changes could last for the rest of their lives, bolstering cognitive abilities and protecting them against degenerative diseases.‘

A 2002 study by Angela Oatridge, from Hammersmith Hospital in London, reported that brain scans of pregnant women showed a 4 per cent decline in size.

Last year, two Australian researchers found that pregnant women consistently performed worse on tests for memory and verbal skills.

But Dr Kinsley believes this is because they are growing new sets of brain cells that he calls ‘maternal circuits’.

Nerve cells in areas known to be linked to parenting also expand and develop more connections with neighbouring cells during pregnancy to give mothers supercharged ‘computing’ power, he said.

He added: ‘Although most studies have so far focused on animals, it is likely women also gain long-lasting benefits from motherhood. Most mammals share similar maternal behaviours controlled by the same brain regions.’

Another study by the University of Toronto has found rats that had given birth were protected against degenerative diseases, with lower levels of a protein linked with Alzheimer’s disease in humans.

And a report by Thomas Perls, associate professor at Boston University medical school, found that women who become pregnant after the age of 40 are four times more likely to live to 100.

Dr Kinsley will report his findings to the Society for Neuroscience’s annual meeting next month.

Source: Daily Mail
http://www.dailymail.co.uk/health/article-1076848/How-mother-boost-brainpower.html

The University of Miami med school is one of the key research sites in a pioneering national study that will examine children’s health from birth to 21.

The University of Miami Medical School will be one of the primary research centers for a 25-year nationwide, pioneering study of children’s health, following potential mothers from before they’re pregnant to when their children reach 21.

The $3.4 billion National Children’s Study, funded by the National Institutes of Health, will track 4,000 children in four Florida counties — including Miami-Dade — and 100,000 nationwide. It will focus on 20 key children’s health issues, including autism, birth defects, heart disease, attention-deficit disorders and obesity.

”We believe it will be the largest study of pregnant women ever conducted — certainly in the United States,” said Dr. Peter Scheidt, director of the national study for the NIH. The NIH will create a national databank of health information on children.

”We won’t have to wait 21 years to benefit,” said Dr. Duane Alexander, director of the National Institute of Child Health and Human Development. “We will release information at each step in the growth process, from pre-conception to 21.”

`THE WHOLE COUNTRY’

Dr. Steven Lipshultz, chairman of pediatrics at UM medical school and Florida principal investigator for the study, says the research will be more significant than the Framingham Heart Study, which has followed a Massachusetts town since 1948 and is seen as the basis for much of what is known about heart disease.

”That was just one Massachusetts town,” he said. “This will cover the whole country.”

Lipshultz estimates the study eventually will create up to 400 medical health jobs in Florida and $400 million of medical spending in Miami-Dade County. UM initially will receive $54.6 million from the NIH to lead the Florida portion of the project. UM will pay participants a range of fees, as yet undetermined.

Miami-Dade, Hillsborough, Orange and Baker are the counties in Florida that will participate in the study — there are 105 counties nationwide.

Lipshultz said he hopes the program can help lift Florida from its ranking of 50th out of 50 states and the District of Columbia in 13 child-health categories according to a May study by the Commonwealth Fund, a private group that studies healthcare issues.

Starting in 2010, if pilot efforts go well, UM researchers will recruit 4,000 families in the four counties.

”We will literally knock on 17,000 doors to get 1,000 children in Miami-Dade,” says Dr. Tracie Miller, associate chair of pediatrics at the UM med school and co-principal investigator of the study.

WATER SAMPLING

Other universities involved are Johns Hopkins University, Baylor College of Medicine, Michigan State University, Northwestern University, Tulane, the University of California at Los Angeles and Vanderbilt.

The studies will follow women from before they conceive, sampling the water they drink, the air they breathe, the schools, shops and workplaces in which they spend time.

Doctors, nurses and medical researchers will look into genetics and environmental factors; psychologists will trace brain development factors that might cause dyslexia, learning disorders, attention-deficit hyperactivity disorder.

Some of the key areas to be studied:

• Birth defects: Birth defects affect one in every 33 babies born in the United States each year, according to the Centers for Disease Control and Prevention. They include heart defects, brain defects and spinal problems such as spina bifida. Birth defects account for more than 20 percent of infant deaths.

• Obesity: Studies by the Florida Governor’s Task Force on Obesity say 10 percent of Florida high school students and 11.5 percent of middle school students are overweight. They say 57.4 percent of Florida adults were overweight or obese, a 63 percent increase since 1986. Early blame was placed on lack of physical activity and poor eating habits.

• Heart disease: Reports by the Florida Department of Health say 39.7 percent of Florida residents said they had high cholesterol in 2005, up from 31 percent in 2001. The report said 26.9 percent engaged in no regular physical activity. And two-thirds of middle school students watched TV or sat at a computer screen for more than three hours a day.

• Autism: The CDC estimates that one in 150 8-year-old U.S. children has an autism spectrum disorder, making up about 560,000 individuals from birth to 21. The number is up from previous decades, possibly because a broader definition of ASD. Some parents believe, despite disagreement from many doctors, that autism might be associated with childhood vaccinations.

The CDC says it does not believe there is a connection.

Says Lipshultz: “There’s no substitute for data.”

Source: MiamiHerald.com
http://www.miamiherald.com/news/miami-dade/story/712697.html

Breastfeeding for longer, cutting out TV and enlisting grandparents to babysit are among the keys to bringing up happy, healthy children, a new Federal Government-funded report shows.

The four-year study measured children’s physical, learning and cognitive development plus social and emotional functioning.

Federal Families, Housing and Community Services Minister Jenny Macklin released the report - Growing Up In Australia: The Longitudinal Study of Australian Children - in Sydney today.

The report shows infants aged three to 19 months had higher learning scores if they were cared for by a range of family and friends - including grandparents - rather than just their parents.

Ms Macklin said grandparents were the unsung heroes of the Australian family unit, providing a strong support base for families by lending a hand with day-to-day family life and influencing their grandchildren’s development.

“This new study demonstrates just what a critical role grandparents play in the development of children,” Ms Macklin told reporters at a daycare centre in inner-city Redfern.

Spending time with grandchildren, reading to them, cooking together and taking them shopping were simple interactions which made the difference, she said.

The only option better than getting grandma and grandpa to babysit was for the children to attend early education programs, the report says.

The study began in 2004 and more than 10,000 families agreed to take part.

Also indicated in the study was that mothers were still not breastfeeding exclusively for long enough.

The National Health and Medical Research Council (NHMRC) recommends mothers breastfeed exclusively for at least six months, but while most of the mothers who had taken part in the study had breastfed, they had not done so for long enough, the results showed.

The majority of children had diets that did not meet nutritional guidelines and many preferred less physical activities.

The lack of breastfeeding also positively correlated to incidences of wheezing in infants and a strong prediction for asthma in children aged four to five.

Perhaps unsurprisingly, children who read more - alone or with a parent - and watched less TV tended towards better developmental scores across the board.

“We know from this study how important it is to a child’s development to … spend as much time as possible everyday reading and spending time playing with children,” Ms Macklin said.

The study also showed that six per cent of children studied lived in households that had been forced to skip meals or not pay bills in order to cope with growing financial stress over the past 12 months.

However, while financial stress had an adverse affect on the child’s development, overall income levels did not - meaning children growing up in affluent households were not necessarily better off than those growing up in poorer homes or neighbourhoods.

The Growing Up in Australia report is the first comprehensive national study of Australian children over time, Ms Macklin said.

Source: The Epoch Times
http://tinyurl.com/4m2nu8

Caesarean childbirth may weaken the attachment of a mother to her baby, a study has shown.

Scientists found women were more emotionally responsive to the cries of their babies if they chose to give birth naturally.
Those who had Caesarean deliveries were significantly less sensitive to the sound of their own babies crying. Parts of their brains believed to regulate emotions, motivation and habitual behaviour were not as strongly activated as they were in natural birth mothers.

Researchers believe the difference may be explained by a “bonding” hormone released in the brain during labour. Oxytocin, known as the “love hormone” or “cuddle chemical”, creates feelings of attachment in both humans and animals. It is also produced in women during breast feeding, and also sex.

Between 10% and 20% of all births in the UK are now delivered by Caesarean section. Controversially, the procedure is linked with post-natal depression.

Caesarean deliveries may be advised for health reasons, but increasingly they are being seen as a “lifestyle choice”. The “too posh to push” tag has been applied in the media to women who pay for private Caesareans. Women who delay motherhood are more likely to have the operation because child birth risks increase with age.

The new research by British and US scientists involved 12 American mothers having their first baby. Six had natural vaginal deliveries and six Caesarean sections. Two to four weeks after the births, the women underwent functional magnetic resonance imaging (fMRI) scans of their brains while listening to the recorded cries of their babies.

The scans revealed a range of brain regions that were more highly activated in natural birth women while hearing the sound of their babies crying. These were parts of the brain that dealt with emotions, empathy, motivation, reward-seeking and habit.
The findings were published in The Journal of Child Psychology and Psychiatry.

Research leader Dr James Swain, from the Child Study Centre at Yale University in New Haven, Connecticut, said: “Our results support the theory that variations in delivery conditions such as with Caesarean section, which alters the neuro-hormonal experiences of childbirth, might decrease the responsiveness of the human maternal brain in the early postpartum.”

Source: The Press Association
http://ukpress.google.com/article/ALeqM5iew4M7SadUR3mNgT69KHn2WSyA_A

For years, new parents have been hearing that “breast is best,” and each decade, more and more women choose lactation as the primary food source for their newborns. It appears that breastfeeding may now produce a generation of smarter, happier babies. Studies have shown that babies need touching and nurturing to develop and survive and breastfeeding supplies both needs on a regular basis.

Breastfed babies followed from birth to 6 years had higher IQ scores than formula-fed babies. This is not a new finding. Past research has shown that mothers from more affluent backgrounds were more likely to breastfeed. Consideration was given to the fact that improved mental abilities may have been related to family circumstance as much as breastfeeding.

Researchers from Canada’s McGill University attempted to overcome the possible influence of family economics by evaluating children born in hospitals in Belarus. The group studied over 13,000 breastfed babies born in 31 maternity hospitals. Some of these hospitals ran breastfeeding promotions to boost rates across all groups. Some provided nursing training and provided support for breastfeeding mothers. The mothers who received the training and continuing support were more likely to nurse for a longer period of time.

The children were divided into groups for evaluation depending on whether their mothers were given nursing training or not. Babies who were exclusively breastfed for the first three months scored 5.9% higher on IQ tests in childhood. Tests indicated that the longer the babies were breastfed the more significant the intelligence difference.

When these children began school teachers also gave them significantly higher academic ratings in both reading and writing than children in control groups. The Archives of General Psychiatry lead researcher Professor Michael Kramer said, “Long-term, exclusive breastfeeding appears to improve children’s cognitive development.” Professor Kramer also said that it was not known if the increased intellectual development was due to some nutritive value of breast milk, or related to the physical and social interactions of breastfeeding.

There are several reasons that breastfeeding may improve the mental development of babies:

* Breast milk contains fatty acids and other nutrients that are necessary for the development of babies.
* Physical and emotional aspects of breastfeeding may lead to permanent improvements in brain development.
* Breastfeeding may increase verbal interaction between mother and child which could aid development.

Though the exact mechanism of improved intelligence as a result of breast feeding is not known there are also other reasons for breastfeeding; children who are breastfed generally have fewer gastrointestinal problems and they have better protection against obesity, diabetes and cancer. Women who breastfeed have a quicker recovery from childbirth and breastfeeding reduces a women’s risk of developing breast cancer.

Breastfeeding is natural and good for the baby and the mother. A pregnant woman who wants to breastfeed but isn’t sure how to began can ask her physician or midwife for a referral to a professional, or any of the many groups who advocate breastfeeding.

Source: HealthNews, CA
http://tinyurl.com/6lvajn

B.C.’s own representative for children and youth says that taking newborns from their mothers while they serve provincial prison time will hurt the children more than sending them to prison.

Mary-Ellen Turpel-Lafond said that mothers and babies benefit enormously from contact — the babies bond with the mothers, and the mothers have a reason to reform.

“I’m very disappointed. It’s a shortsighted move,” saidTurpel-Lafond, adding that wrecking the family unit would encourage more criminal behaviour in the parents and the kids.

“What’s the cost to society of those children going into care and severing that bond?” she asked.

The provincial government quietly cancelled a pilot program that allowed 12 mothers to either give birth to babies in custody or bring newborns to prison with them.

Though the government would not comment to CTV News on the move, the reasons that were given were about safety of the babies.

The children are kept in a special unit of Alouette Correctional Centre for Women in Maple Ridge, with other women who are chosen for the program.

But Turpel-Lafond said she had interviewed several of the women and reviewed the program and found that there was little risk.

“I’ve had a chance to meet some of the moms and to advocate for some of the babies. That type of brain development is happening. To sever that, to put them with a caregiver and a foster parent is far more harmful to the child than any harm that might be posed in an institution.

“In fact, I’ve never heard of any,” she said.

The representative for children and youth is an independent body in B.C.’s government that looks out for children.

The province is risking the recovery of other pregnant moms in the correctional system, she said.

“There are pregnant moms who need that program now and I don’t want to see the babies removed,” she said.

Jennifer Smith, 24, gave birth while in custody at Alouette Correctional Centre for Women. She said the chance to keep her baby made her want to change her ways.

“I had a child,” she told CTV News. “That’s basically the only thing that changed my life.”

There is still a federal program that allows babies in certain prisons.

Source: CTV British Columbia, Canada
http://tinyurl.com/6fjse4

Being born underweight leads to a shy and cautious wallflower-type personality, a McMaster University researcher has found.

People who feel inhibited in social situations, aren’t as talkative and are more anxious about taking risks, may not get these traits from their upbringing, said Louis Schmidt, lead author of the recent study and a professor of psychology, neuroscience and behaviour.

Such timidness potentially affects a person’s future and could lead to “delays in occupational obtainment, delays marrying and having children,” he added.

The study, which was published in the July issue of Pediatrics, harks back to the nature versus nurture debate about how someone’s personality gets developed.

“What plays a bigger role?” he asked. “We’re looking at how early life events and early experiences impact brain development.”

Schmidt hypothesized these personality traits could be because the underweight babies spent so much time in a neonatal unit - some for months at a time - and didn’t get the same chance to bond with their parents as normal-weight babies.

Underweight babies also are at risk for other medical problems, like compromised immune systems, and tend to face a higher rate of diabetes and heart disease as adults.

This study looked at 71 young adults, born in southern Ontario in the late 1970s and early 1980s who were underweight at birth, and compared them to 83 people who were born around the same time and region at a normal weight.

The young adults were asked a series of questions about how social they are and how likely they are to take risks.

Underweight babies typically weigh less than 2,500 grams (5.5 pounds). In Canada, one of every 16 babies are born underweight.

Schmidt’s study found the lower the birth weight, the more shy and inhibited the person is as an adult.

They have also been studying brain activity and hormones in these young adults, both those who were born underweight and at a normal weight.

The findings, which are currently under review, show being born underweight could also lead to an inability to handle stress, Schmidt said.

Source: Hamilton Spectator, Canada
http://www.thespec.com/News/Local/article/410333